Therapeutic Class

Tri-Heart® Plus Chewable Tablets

Tri-Heart® Plus (ivermectin/pyrantel) is a proven, cost-effective and easy-to-administer chewable tablet that helps keep your dog free of heartworm and other dangerous parasites.1

Dogs of any age, even older dogs, can become infected with heartworms, roundworms or hookworms that can rob their vitality and shorten their lifespan.

Tri-Heart Plus chewable tablets contain a proven combination of ingredients to protect your dog and ensure your complete peace of mind. Ask your veterinarian about Tri-Heart Plus today.

How to Administer

Give your dog one beef-flavored chewable Tri-Heart Plus tablet on the same day each month. Dogs that are on a preventive medicine should also be tested routinely to ensure protection, especially if a dose has been missed or forgotten.


100% Satisfaction Guarantee

When Tri-Heart Plus is obtained from a licensed veterinary practitioner with a veterinarian/client/patient relationship, our guarantee covers:

  • Effective prevention of heartworm disease
  • Reliable treatment and control of hookworms and roundworms
  • Acceptance of our flavored chewable tablets

Call 1-800-224-5318 if you have any additional questions regarding the Tri-Heart Plus guarantee.

Product Information1

Chewable Tablets
Brief Summary: Please consult the full package insert for more information.

INDICATIONS: Tri-Heart Plus chewable tablets are indicated for use in prevention of canine heartworm caused by Dirofilaria immitis and for the treatment and control ofascarids (Toxocara canis, Toxascaris leonina) and hookworms (Ancylostoma caninum, Uncinaria stenocephala, Ancylostoma braziliense) in dogs and in puppies six weeks of age.

ADVERSE REACTIONS: The following adverse reactions have been reported following the use of ivermectin at the recommended dose: depression/lethargy, vomiting,anorexia, diarrhea, mydriasis, ataxia, staggering, convulsions and hypersalivation.

CAUTION: Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian.

HOW SUPPLIED: Tri-Heart Plus chewable tablets are available in three dosage strengths for dogs of different weights. Each strength comes in convenient packs of 6 chewable tablets.

Store at controlled room temperature of 59-86° F (15-30° C). Protect product from light.

For technical assistance, call Merck Animal Health at 1-800-224-5318.

All dogs should be tested for heartworm infection before starting a preventive program. In a small percentage of ivermectin/pyrantel-treated dogs, digestive and neurological side effects may occur.


1.  Freedom of Information Summary, ANADA 200-338. Approved August 13, 2003