Nobivac® Feline 1-HCP+FeLV



Feline Leukemia, Rhinotracheitis, Calici, Panleukopenia Vaccine, MODIFIED LIVE AND KILLED VIRUS


The only combination vaccine that provides 2-year duration of immunity1 for feline leukemia virus (FeLV) in addition to 1-year protection against feline rhinotracheitis, calicivirus, and panleukopenia.

Features and benefits

  • A quality core vaccine that protects against feline rhinotracheitis, feline panleukopenia virus (FPV), and feline calicivirus (FCV), in addition to providing extensive 2-year coverage for FeLV
  • Nobivac® Feline 1-HCP has been shown to block the replication of canine parvovirus (CPV) in cats1
    • Evidence shows that CPV-2a, CPV-2b, and CPV-2c isolates can replicate in cats, producing clinical signs of feline panleukopenia2-4
  • The only feline leukemia vaccine labeled to prevent persistent viremia for 2 years after vaccination5
  • Superior Efficacy demonstrated vs. multiple FeLV vaccines6,7
    • The ONLY USDA-licensed 2-Year Duration of immunity (DOI) FeLV vaccine1,5 (Ideal for adherence to AAFP guidelines8)
    • The ONLY vaccine to demonstrate efficacy over the long-term in a co-mingling study mimicking real life conditions1
  • Proven safety profile- 99% reaction-free in ongoing surveillance involving millions of doses1
  • The optimal choice for both indoor.outdoor cats of all ages and for all cats under 1 year of age

Indication

  • Approved for the vaccination of healthy cats as an aid in the prevention of disease caused by feline rhinotracheitis, calici, and panleukopenia viruses
  • Approved as an aid in the prevention of lymphoid tumors caused by, and diseases associated with feline leukemia virus (FeLV) infection
  • Vaccination with this product prevents persistent viremia in cats exposed to virulent FeLV
  • Recommended for use in healthy cats 9 weeks of age or older

Safety information

  • 98.8% reaction-free in field safety studies
  • 99.99% reaction-free in ongoing surveillance involving millions of doses1
  • Study showed no signs of inflammation or adjuvant at Day 21 after subcutaneous vaccination1
  • Two-year DOI means fewer vaccinations

Please see the product label for safety information.

Administration and Dosage

For cats 9 weeks of age or older:

  • Subcutaneous or intramuscular injection
  • Initial 1-mL dose administered at 9 weeks of age or older
  • Second 1-mL dose administered 3 to 4 weeks later
  • Revaccination every 2 years with 1 dose of Nobivac® Feline 1-HCP+FeLV is recommended
  • Revaccination in the intervening years with Nobivac® Feline 1-HCP is recommended

For further information, including complete directions and warnings, please see the product label.

Product label(s) and MSDS

References:

  1. Data on file, Merck Animal Health.
  2. Hoelzer K, Parrish CR. The emergence of parvoviruses of carnivores. Vet Res. 2010;41(6):39.
  3. Ikeda Y, Nakamura K, Miyazawa T, Takahashi E, Mochizuki M. Feline host range of canine parvovirus: recent emergence of new antigenic types in cats. Emerg Infect Dis. 2002;8(4):341–346.
  4. Truyen U. Emergence and recent evolution of canine parvovirus. Vet Microbiol. 1999;69(1–2):47–50.
  5. Jirjis FF, Davis T, Lane J, et al. Protection against feline leukemia virus challenge for at least 2 years after vaccination with an inactivated feline leukemia virus vaccine. Vet Ther. 2010;11(2):E1–E6.
  6. Torres AN, O'Halloran KP, Larson LJ, Schultz RD, Hoover EA. Feline leukemia virus immunity induced by whole inactive virus vaccinaton. Vet Immunol Immunopathol. 2010; 134 (1-2): 122-131
  7. Patel M, Carritt K, Lane J, Jayappa H, Stahl M, Bourgeois M. Comparative efficacy of feline leukemia virus inactivated whole virus vaccine and canarypox virus-vectored vaccine during virulent FeLV challenege and immunosuppresson. Clin Vaccine Immunol. 2015
  8. American Association of Feline Practitioners. AAFP 2013 feline vaccination advisory panel report. J Feline Med Surgery.2013; 15:785-808