BRAVECTO® PLUS (fluralaner and moxidectin topical solution) for Cats is the solution for fleas, ticks, heartworm and intestinal parasites in ONE easy, 2-month topical. Specifically designed for the challenges of treating cats, BRAVECTO PLUS delivers everything that you expect from BRAVECTO and more.
INDICATIONS:
Bravecto Plus is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment of infections with intestinal roundworm (Toxocara cati; 4th stage larvae, immature adults and adults) and hookworm (Ancylostoma tubaeforme; 4th stage larvae, immature adults and adults). Bravecto Plus kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick) and Dermacentor variabilis (American dog tick) and Haemaphysalis longicornis (Asian longhorned tick)] for 2 months in cats and kittens 6 months of age and older and weighing 2.6 lb or greater.
Small cats
2.6—6.2 lbs
Medium cats
>6.2—13.8 lbs
Large cats
>13.8—27.5 lbs†
One application/tube per weight band
The 2-month efficacy of a single dose of BRAVECTO PLUS against Ctenocephalides felis fleas has been confirmed in laboratory studies.1
Residual speed of kill and persistent efficacy against fleas (C. felis)1
Efficacy against fleas was 100% within 12 hours and > 99% for 2 months.1
Efficacy against ticks (Ixodes scapularis and Dermacentor variabilis)2
Innovative approach to heartworm (Dirofilaria immitis) disease prevention3
BRAVECTO PLUS was 100% effective against heartworm disease for 2 months. Uniquely, in the studies, the cats were treated 60 days before 3rd stage larval infection, thereby proactively protecting the cats.3
Efficacy against roundworms (Toxocara cati) for 2 months4
In well-controlled laboratory studies, BRAVECTO PLUS was effective against naturally and experimentally induced adult and experimentally induced 4th stage larval and immature adult Toxocara cati infection in cats.5
Efficacy against hookworms (Ancylostoma tubaeforme) for 2 months6
In well-controlled laboratory studies, BRAVECTO PLUS was effective against naturally and experimentally induced adult and experimentally induced 4th stage larval and immature adult Ancylostoma caninum infection in cats.5
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Recommend the feline flea and tick topical that is indicated for internal and external parasites, and lasts twice as long as monthly products.
Easy for Cat Owners
A 2-month topical that combines flea and tick protection, treatment of intestinal parasites, and heartworm prevention can be easier on cat owners than monthly doses of multiple products.
Creates Less Stress
An extended duration product can help ease the stress on cats and their owners.
Encourages Compliance
Less frequent application may lead to fewer gaps in protection.7-9
Increases Length of Protection
Using a 2-month product can increase the overall number of months of coverage.7-9
Fits Scientific Recommendations
The Companion Animal Parasite Council (CAPC) recommends year-round protection for cats against fleas, ticks, heartworm, roundworms, and hookworms.10
In addition to the studies supporting the efficacy and safety of BRAVECTO PLUS, our BRAVECTO portfolio of published studies can be found at Parasites & Vectors in the Bravecto collection.
Contact us for more information about BRAVECTO PLUS for your hospital.
We can answer all your questions, and get you started prescribing BRAVECTO PLUS
for the felines in your care.
For technical assistance or to report a suspected adverse drug reaction, contact Merck Animal Health at
1-800-224-5318.
This site is intended for veterinary professionals. Visit our website for pet parents.
*BRAVECTO kills fleas and prevents flea infestations. BRAVECTO (fluralaner) Chews for Dogs kills ticks (black-legged tick, American dog tick, brown dog tick, and Asian longhorned tick) for 12 weeks. BRAVECTO Chews also kills lone star ticks for 8 weeks. BRAVECTO (fluralaner topical solution) for Dogs kills ticks (black-legged tick, American dog tick, and brown dog tick) for 12 weeks. BRAVECTO Topical Solution for Dogs also kills lone star ticks for 8 weeks. BRAVECTO (fluralaner topical solution) for Cats kills ticks (black-legged tick and Asian longhorned tick) for 12 weeks. BRAVECTO Topical Solution for Cats also kills American dog ticks for 8 weeks
IMPORTANT SAFETY INFORMATION
BRAVECTO 1-MONTH (fluralaner) Chews: indicated for dogs 8 weeks of age and older. The most commonly reported adverse reactions include itching, diarrhea, vomiting, decreased appetite, elevated ALT, lethargy, and weight loss. BRAVECTO 1-MONTH is not effective against A. americanum in puppies less than 6 months of age. BRAVECTO (fluralaner) Chews for Dogs: The most commonly reported adverse reactions include vomiting, lethargy, diarrhea, anorexia and pruritus. In some cases, adverse events have been reported following use in breeding females. BRAVECTO (fluralaner topical solution) for Dogs: The most commonly reported adverse reactions include vomiting, hair loss, diarrhea, lethargy, decreased appetite, and moist dermatitis/rash. BRAVECTO (fluralaner topical solution) for Cats: The most commonly reported adverse reactions include vomiting, itching, diarrhea, hair loss, decreased appetite, lethargy, and scabs/ulcerated lesions. BRAVECTO Topical Solution for Cats is not effective against American dog ticks beyond 8 weeks of dosing. BRAVECTO PLUS (fluralaner and moxidectin topical solution) for Cats: The most commonly reported adverse reactions include vomiting, hair loss, itching, diarrhea, lethargy, dry skin, elevated ALT, and hypersalivation. BRAVECTO PLUS has not been shown to be effective for 2 months in kittens less than 6 months of age. Use with caution in cats that are heartworm positive. The effectiveness of BRAVECTO PLUS to prevent heartworm disease after bathing or water immersion has not been evaluated.
BRAVECTO Chews and Topical Solution for dogs have not been shown to be effective for 12-weeks’ duration in puppies or kittens less than 6 months of age. BRAVECTO Chews and Topical Solution for Dogs are not effective against the lone star tick beyond 8 weeks of dosing. BRAVECTO Topical Solution for Dogs and Cats and BRAVECTO PLUS for Cats are for topical use only. Avoid oral ingestion. The safety of BRAVECTO Topical Solution for Cats and BRAVECTO PLUS have not been established in breeding, pregnant and lactating cats.
All BRAVECTO products contain fluralaner, which is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. Neurologic adverse reactions have been reported in cats receiving isoxazoline class drugs, even in cats without a history of neurologic disorders. Use with caution in cats with a history of neurologic disorders.
References:
1. BRAVECTO PLUS [prescribing information]. Madison, NJ: Intervet Inc. (d/b/a Merck Animal Health); 2019.
2. BRAVECTO PLUS FOI, NADA 141-518. (Studies S15312-03, 15311-01).
3. BRAVECTO PLUS FOI, NADA 141-518. (Studies S15102-01, S15102-03).
4. BRAVECTO PLUS FOI, NADA 141-518. (Studies S15214-02, S15313-00, S15356-00, S15187-00).
5. BRAVECTO PLUS FOI, NADA 141-518. (Study S15318-00).
6. BRAVECTO PLUS FOI, NADA 141-518. (Studies S15138-00, S15214-02, S15313-00, S15355-00).
7. Lavan RP et al. Parasites & Vectors. 2017; 10:284.
8. Lavan RP et al. Parasites & Vectors. 2018; 11:581.
9. Brakke Consulting. The US Flea Control and Heartworm Markets. 2018:6-7.
10. CAPC website. Intestinal Parasite Guidelines. Found at www.capcvet.org. Accessed July 11, 2019.
Revolution PLUS is a registered trademark of Zoetis Services LLC.
