THE BORRELIACIDAL DIFFERENCE
Only Nobivac® Lyme induces borreliacidal activity against both OspA and OspC1,5,80 Not all antibody responses are the same.
- “Multi-Osp protection” that induces antibodies against Osps other than OspA and OspC has not been shown to be relevant5,29,30
- Other Lyme vaccines may induce antibodies against OspC, but they are not borreliacidal—meaning they don’t kill Borrelia burgdorferi
- As a result, vaccines that only induce borreliacidal antibodies against OspA provide incomplete protection once OspC becomes the dominant protein expressed in the tick
- Only Nobivac® Lyme induces OspC borreliacidal antibodies that kill spirochetes in the tick midgut, those migrating from the midgut to the tick’s salivary glands, and those introduced into the dog80