Learn More About Dosing & Administration
How to Administer Using a U-40 Insulin Syringe
Use these step-by-step instructions to teach your clients how to administer Vetsulin® (porcine insulin zinc suspension) to their dog from the comfort of home.
Important Dosage Information
Doses of insulin are measured in units: 40 IU/mL insulin contains 40 International Units (IU) per milliliter (mL) (1 mL = 1 cc).
Use Vetsulin with U-40 insulin syringes only to avoid dosing errors when administering Vetsulin to dogs. Human insulin is formulated at a concentration of 100 IU/mL. Using a U-100 insulin syringe, would result in a dog receiving two and a half times less insulin than required, resulting in inadequate dosing and likely recurrence of signs.
Clients may attempt to replenish their syringe inventories and/or insulin supply from their local human pharmacies. Most pharmacists are not aware of Vetsulin, VetPen, or the U-40 insulin syringes, nor do they stock these items. As this potential situation can result in dysregulation, it is strongly advised to educate clients to purchase both Vetsulin and the U-40 insulin syringes from your veterinary clinic.
Preparing the Dose
After washing your hands, take the Vetsulin (porcine insulin zinc suspension) vial out of the refrigerator. Shake the vial until the insulin is uniformly milky, allowing any foam to disperse.
- Carefully remove the cap from the needle and insert the needle into the vial.
- Turn the vial upside down, making sure the tip of the needle remains in the vial.
- Withdraw the correct dose into the U-40 insulin syringe.
- Before removing the needle from the vial, check the syringe for any air bubbles.
- If bubbles are present, hold the syringe up and tap its side until the bubbles float to the top. Push them out with the plunger and withdraw the correct dose.
- Remove the needle from the vial.
Giving the Injection
- Injection should be given under the skin, 3/4 to 2 inches from the middle of your dog’s back, varying from behind the shoulder blades to the middle of the back region and alternating sides.
- Gently insert needle in center of folded skin.
- Push plunger until all of the insulin is given.
- Pull needle out and dispose of syringe into appropriate sharps collector.
- Injection site can depend upon what is best for the client and their dog.
- Alternate injection site between left and right side for comfort and best results. Repeat injections at the same site can lead to ineffective treatment.
- Instructing clients to record the location of administration can help assure site rotation.
- If only a partial dose is given, do not attempt to re-dose. Wait and give the dog it’s usual dose at the next injection time.
Downloadable Vetsulin® Instructions
A helpful PDF to help clients prepare and administer Vetsulin to their dogs.
Help Your Practice Manage Diabetes Mellitus
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Learn More About Dosing & Administration
Important Safety Information:
Vetsulin® should not be used in dogs known to have a systemic allergy to pork or pork products. Vetsulin is contraindicated during periods of hypoglycemia. Keep out of reach of children. As with all insulin products, careful patient monitoring for hypoglycemia and hyperglycemia is essential to attain and maintain adequate glycemic control and prevent associated complications. Overdosage can result in profound hypoglycemia and death. The safety and effectiveness of Vetsulin in puppies, breeding, pregnant, and lactating dogs has not been evaluated. See package insert for full information regarding contraindications, warnings, and precautions.
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