WHY IT WORKS
A unique active ingredient makes ZUPREVO® (tildipirosin) effective, flexible and convenient.
ZUPREVO belongs to a class of antibiotics known as macrolides. Our active ingredient, tildipirosin, is a tri-basic, 16-member macrolide. This unique molecular structure allows ZUPREVO to act faster and last longer than competing BRD products.
Works against major
BRD-causing bacteria.
| Mannheimia haemolytica |
| Pasteurella multocida |
| Histophilus somni |
ZUPREVO excels where it matters.
When it comes to treating BRD and controlling respiratory disease, you want a product that acts fast, keeps working and delivers a big dose of BRD-fighting active ingredient to the lungs. Tildipirosin’s 16-member macrolide structure allows ZUPREVO to do all three.
FAST-ACTING
Reaches peak plasma levels just 45 minutes after administration.2
LONG-LASTING
28 days*1 in the lungs. 21 days*1 in the bronchial fluid.
HIGH CONCENTRATION
Concentrates in the lungs and bronchial fluid, allowing extensive distribution.
*The correlation between pharmacokinetic data and clinical effectiveness is unknown.
Bactericidal Activity of Tildipirosin
Get the BRD treatment that goes to work fast, and stays working longer.
1 Menge M. et al. Pharmacokinetics of tildipirosin in bovine plasma, lung tissue, and bronchial fluid (from live, non-anesthetized cattle). J Vet Pharm Ther. Doj: 10.1111/J. 1365-2885, 2011. 1349.x.
Important Safety Information
FOR USE IN ANIMALS ONLY. NOT FOR HUMAN USE. KEEP OUT OF REACH OF CHILDREN. TO AVOID ACCIDENTAL INJECTION, DO NOT USE IN AUTOMATICALLY POWERED SYRINGES WHICH HAVE NO ADDITIONAL PROTECTION SYSTEM. IN CASE OF HUMAN INJECTION, SEEK MEDICAL ADVICE IMMEDIATELY AND SHOW THE PACKAGE INSERT OR LABEL TO THE PHYSICIAN.
RESIDUE WARNING: Cattle intended for human consumption must not be slaughtered within 21 days of the last treatment. Do not use in female dairy cattle 20 months of age or older. Use of this drug product in these cattle may cause milk residue. A withdrawal period has not been established in pre-ruminating calves. Do not use in calves to be processed for veal.
The effects of ZUPREVO® 18% on bovine reproductive performance, pregnancy and lactation have not been determined. Swelling and inflammation, which may be severe, may be seen at the injection site after administration. Subcutaneous injection may result in local tissue reactions which persist beyond slaughter withdrawal period. This may result in trim loss of edible tissue at slaughter.
DO NOT USE ZUPREVO® 18% IN SWINE. FATAL ADVERSE EVENTS HAVE BEEN REPORTED FOLLOWING THE USE OF TILDIPIROSIN IN SWINE. NOT FOR USE IN CHICKENS OR TURKEYS.
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