ESTRUMATE® delivers proven performance that can redefine what you expect from a prostaglandin. With an active ingredient featuring a significantly longer half-life than LUTALYSE® (dinoprost tromethamine injection), research has demonstrated that ESTRUMATE® delivers superior reproductive performance.1,2
The ESTRUMATE Edge compared to a single injection of LUTALYSE.1,2,3,4
The M-Power Advantage when using herd monitoring for targeted synchronization.1,2
Maximize dairy herd fertility with Targeted Reproductive Management.
Monitoring technology or hormones? The best results come when you combine both.
It’s called Targeted Reproductive Management. By leveraging the individualized insights provided through SenseHub® Dairy monitoring technology, you can use hormones on only the cows who need them to take repro efficiency to a whole new level.
Detect
heats precisely
With SenseHub Dairy monitoring, you can make decisions with unmatched heat detection accuracy and precise insemination timing guidance.
Identify estrus
synchronization candidates
Monitoring reports reveal which cows showed weak or no signs of estrus during the voluntary waiting period after calving. Those cows are then automatically enrolled in a fertility program.
Use hormones
judiciously
Decrease hormone use while increasing their effectiveness. One of the many benefits of this approach is the ability to strategically administer reproductive hormones to the right cows at the right time, giving them the best chance of success.
Important Safety Information
ESTRUMATE: Do not administer ESTRUMATE to a pregnant cow unless abortion is desired. Severe localized post-injection clostridial infections have been reported; in rare instances infection has led to death. Women of childbearing age, asthmatics, and persons with respiratory problems should exercise extreme caution when handling ESTRUMATE. ESTRUMATE is readily absorbed through the skin and can cause abortion and/or bronchospasms; direct contact with the skin should be avoided, and accidental spillage on the skin should be washed off immediately with soap and water. For complete safety information, refer to the product label.
References
- Veronese A, Marques O, Moriera R, Belli AL, Bilby TR, Chebel RC. Estrous characteristics and reproductive outcomes of Holstein heifers treated with 2 prostaglandin formulations and detected in estrus by an automated estrous detection or mounting device. J Dairy Sci 2019:102(7):6649-6659.
- Umaña Sedó SG, Figueiredo CC, Gonzalez TD, Duarte GA, Ugarte Marin MB, Crawford CA, Pohler KG, Chebel RC, Bilby TR, Bisinotto RS. Evaluation of luteolysis, follicle size, and time to ovulation in Holstein heifers treated with two different analogs and doses of prostaglandin-F2α. J Dairy Sci 2022 Jun;105(6):5506-5518.
- Chebel RC, Gonzalez T, Montevecchio AB, Galvão KN, de Vries A, Bisinotto RS. Targeted reproductive management for lactating Holstein Cows: Economic return. J Dairy Sci Feb 2025;108(2):1584-1601.
- Pursley JR, Martins JPN, Wright C, Steward ND. Compared to dinoprost tromethamine, cloprostenol sodium increased rates of estrus detection, conception, and pregnancy in lactating dairy cows on a large commercial dairy. Therio 2012:78(5):823-829.