Pasteurella haemolytica and Pasteurella multocida

Disease Overview

A respiratory disease that affects cattle, it is often seen combined with bacterial infections.

Merck Animal Health Solutions

For Pasteurella haemolytica and Pasteurella multocida

NUFLOR (florfenicol) is an injectable antibiotic indicated for treatment of bovine respiratory disease (BRD) (with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni), bovine interdigital phlegmon (with Fusobacterium necrophorum and Bacteroides melaninogenicus) in cattle.

Shown to be effective for the vaccination of healthy cattle 3 months of age or older against disease caused by Pasteurella multocida and Mannheimia haemolytica.

RESFLOR GOLD (florfenicol and flunixin meglumine) is a simple bovine respiratory disease (BRD) treatment strategy. It involves a combination of two therapies in one dose: the powerful antibiotic florfenicol to kill or inhibit the disease-causing bacteria Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Mycoplasma bovis; and, the fast-acting non-steroidal anti-inflammatory drug (NSAID) flunixin meglumine to reduce BRD-associated fever.

Shown to be effective for the vaccination of healthy cattle 3 months of age or older against respiratory disease and abortion due to infectious bovine rhinotracheitis (IBR), respiratory disease and fetal infection, including persistently infected calves due to bovine virus diarrhea virus (BVD) Types 1 and 2, bovine respiratory syncytial virus (BRSV), parainfluenza3 virus (PI3), Mannheimia Haemolytica and Pasteurella multocida. Respiratory duration of immunity has been shown to be at least 1 year for IBR and BVD (Types 1 and 2) and at least 16 weeks for Mannheimia haemolytica and Pasteurella multocida. Reproductive duration of immunity has been shown to be at least 217 days for IBR and at least 206 days for BVD (Types 1 and 2). Duration of immunity for BRSV and PI3 has not been established.Respiratory and reproductive efficacy and duration of immunity has been demonstrated against disease caused by the BVD Type 1b strain.

Clinical Signs

  • Depression
  • Fever
  • Nasal discharge
  • Moist cough
  • Rapid, shallow breathing