Shown to be effective for the vaccination of healthy cattle and sheep against disease caused by Clostridium chauvoei (Blackleg), Cl. septicum (Malignant edema), Cl. haemolyticum (Bacilliary Hemoglobinuria (Red water)), Cl. novyi (Black disease), Cl. sordellii and Cl. perfringens Types C and D (Enterotoxemia).