Canine 1-DAPPvL2

A proven, combined vaccine that protects dogs against several highly contagious viruses and 2 leptospira serovars.

It’s time to Pair Up for Protection

Canine Distemper Virus, Canine Adenovirus Type 2, Canine Parainfluenza Virus, Canine Parvovirus (modified live viruses), and Leptospira Canicola-Icterohaemorrhagiae (inactivated bacterin).

  • Protects against all known strains of canine parvovirus (CPV), including CPV-2c2,3
    • Contains CPV-2b, one of the most prevalent field strains of parvovirus
    • High antigenic mass (titer), low passage parvovirus vaccine
    • Overrides maternal antibodies in young puppies1
  • Defends against 2 strains of Leptospira: L. canicola and
    L. icterohaemorrhagiae
  • Protects against 2 types of adenovirus that cause hepatitis and respiratory disease in dogs
  • Provides disease coverage for commonly spread canine viruses, distemper, adenovirus types 1 and 2, parainfluenza and parvovirus, in 1 formula


Shown to be effective for vaccination of healthy dogs 6 weeks of age or older against canine distemper virus,canine adenovirus type 1(hepatitis), canine adenovirus type 2 (respiratory disease), canine parainfluenza virus, canine parvovirus, Leptospira canicola and Leptospira icterohaemorrhagiae.

Recommended for use in healthy dogs 6 weeks of age or older.


  • Subcutaneous or intramuscular injection
  • Two 1 mL doses given 2 to 4 weeks apart
  • Two doses are required for primary immunization
  • Contact your veterinarian or manufacturer for more information on revaccination frequency
  • Available in a 25 x 1 mL dose presentation

Professional Resources and Educational Materials

Keep your clinic and staff informed and aware of diseases and outbreaks.

Quick Guide to Lepto


A handy guide to protect dogs and prevent the spread of leptospirosis.

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Nobivac® Social Media Kits

Digital Assets

Use these ready-to-share posts to educate pet parents and drive business to your clinic for preventative care.

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AAHA Canine Vaccination Guidelines


In-depth information about canine vaccinations and veterinary best practices.


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