BOVILIS® NASALGEN® 3

BOVILIS® NASALGEN®

Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Vaccine

Product Description

The color of longer IBR protection.
BOVILIS^® NASALGEN^® 3 offers young calves an unrivaled BRD defense. With 195 days of IBR protection plus BRSV and PI₃, BOVILIS NASALGEN 3 is the insurance you need to give your young calves the strong foundation they deserve. And with a unique BluShadow^®, there’s no second guessing which animals have been vaccinated.

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Indications

This product has been shown to be effective for the vaccination of healthy cattle, 1 week of age or older against infectious bovine rhinotracheitis (IBR) virus, bovine respiratory syncytial virus (BRSV) and parainfluenza 3 virus (PI₃). Duration of immunity against IBR is at least 195 days, against BRSV is at least 78 days, and against PI₃ is at least 95 days.

Diseases

Infectious bovine rhinotracheitis (IBR)
Bovine respiratory syncytial virus (BRSV)
Parainfluenze 3 (PI₃)

Key Benefits

Designed with IBR strains that are not temperature-sensitive.¹ Ensures the vaccine will replicate and protect in any situation.
Unique BluShadow® diluent for confident administration.
Proven safe in pregnant cows and in calves nursing pregnant cows.

Long-lasting Duration of Immunity

195 days against IBR
95 days against PI₃
78 days against BRSV

A Game-changing Vaccine

nnovation is critical in vaccine development. For decades it was believed that vaccinating young animals was not effective because of maternal antibody interference. The industry needed to find a way to protect young calves from BRD.

Learn from members of the team who brought to market BOVILIS NASALGEN 3-PMH — the first and only intranasal BRD vaccine offering protection against viral and bacterial pathogens.

Dosage

Shake well and administer a 2 mL dose by the intranasal route. For advice on revaccination frequency, contact your veterinarian.

Supplied

20 mL x 10 doses (2 mL per dose)
25 mL x 1 dose/2 mL x 25 doses (2mL per dose)
100 mL x 50 doses (2 mL per dose)

Caution

Store at 2 to 8°C (35 to 46°F). Fetal health risks associated with the vaccination of pregnant animals with this vaccine cannot be unequivocally determined during clinical trials conducted for licensure. Appropriate strategies to address the risks associated with vaccine use in pregnant animals should be discussed with a veterinarian. Use entire contents when first opened. Do not use chemical disinfectants to sterilize syringes or needles. Do not mix with other products, except as specified on the label. Inactivate unused contents before disposal. Do not vaccinate within 21 days of slaughter. Anaphylactoid reactions may occur following use. Antidote: Epinephrine. Contains Penicillin and Streptomycin as a preservative. In case of human exposure, contact a physician.
FOR ANIMAL USE ONLY.

Research

Efficacy of the Infectious Bovine Rhinotracheitis Fraction of Nasalgen® 3 in Calves 4 to 7 Days Old

Efficacy of the Bovine Respiratory Syncytial VirusFraction of Nasalgen® 3 in Calves 4 to 7 Days Old

Efficacy of the Bovine Parainfluenza 3 Virus Fractionof Nasalgen® 3 in Calves 6 or 7 Days Old

Duration of Immunity of the Infectious BovineRhinotracheitis Virus Fraction of Nasalgen® 3in Calves 3 to 5 Days of Age

Duration of Immunity of the Bovine RespiratorySyncytial Virus Fraction of Nasalgen® 3in Calves 5 to 7 Days of Age

Duration of Immunity of the Parainfluenza 3 Fractionof Nasalgen®Key Highlights 3 in Calves 3 to 5 Days of Age

Contact

U.S. only: Merck Animal Health livestocktechsrvc@merck-animal-health.com or call 1-800-211-3573
For more information regarding efficacy and safety data, go to productdata.aphis.usda.gov
For additional information, please see the product label.

References

Grissett GP, et al. Effect of Ambient Temperature on Viral Replication and Serum Antibody Titers Following Administration of a Commercial Intranasal Modified-Live Infectious Bovine Rhinotracheitis-Parainfluenza-3 Virus Vaccine to Beef Cattle Housed in High- and Moderate-Ambient Temperature Environments. Am J Vet Res. 2014;75(12):1076-1082.

The dry period is an important time to minimize mastitis risk and vaccinate cows to protect their calves from scours. Give your dry cows the complete care they deserve.

Dry cow