BRAVECTO® Quantum

1 quick injection. 1 full year* of flea and tick protection for dogs.1

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Product Description

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Take control with year-long* protection that’s only administered by veterinary professionals like you.

Only BRAVECTO QUANTUM utilizes a unique, patented composition of fluralaner, one of the world’s most trusted flea and tick medications.

Administered subcutaneously via aqueous suspension

The extended-release composition delivers effective levels of fluralaner for 12 months1*

We stand behind our products with our BRAVECTO Brand Promise

Compliance in your hands

Discover how BRAVECTO QUANTUM empowers veterinarians to improve pet owner compliance by ensuring protection is delivered in the clinic.

Indications

BRAVECTO QUANTUM kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and for the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick) and Rhipicephalus sanguineus (brown dog tick)] for 12 months in dogs and puppies 6 months of age and older.

BRAVECTO QUANTUM is also indicated for the treatment and control of Amblyomma americanum (lone star tick) infestations for 8 months in dogs and puppies 6 months of age and older.

Kills fleas and ticks for a full year* in dogs 6 months of age or older with a single injection.

Cat Flea – ctenocephalides felis

Black-legged tick – ixodes scapularis

Brown Dog Tick – rhipicephalus sanguineus

American Dog Tick – dermacentor variabilis

Lone Star Tick – amblyomma americanum*

The first single-dose year-long flea protection

BRAVECTO QUANTUM prevents flea infestations by killing fleas before they can lay eggs.

Why year-round protection matters

Veterinarians discuss the critical need for continuous parasite protection and how BRAVECTO QUANTUM makes 12 months* of coverage easy with just 1 dose.

100% effective against adult fleas by 48 hours after treatment2

Onset of efficacy study against ctenocephalides felis (cat flea)2 ✝

✝ Onset of efficacy is defined as the time following treatment administration to achieve a ≥90% reduction in live flea counts.
‡ Flea counts are in arithmetic means. Percent effectiveness is based on arithmetic means.

≥99.7% effective against adult fleas 24 hours post-infestation from 1 week through 12 months after treatment2

Flea efficacy-adulticide2 §

§ Flea counts are arithmetic means. Percent effectiveness is based on arithmetic means.

100% effective in eliminating egg production for 365 days2

Flea efficacy-egg production2 ||

|| Flea egg counts are arithmetic means.

The most extended efficacy against serious tick-borne threats

BRAVECTO QUANTUM provides the longest-lasting tick protection available in a single dose.1

A full year* of confidence

With its long-lasting protection, BRAVECTO QUANTUM seamlessly aligns with annual preventives, exams, and vaccines—helping pet parents stay on track with their dog’s care.

Remained ≥94% effective against Rhipicephalus sanguineus from Day 7 through Day 3652

Duration of efficacy studies against R sanguineus (Brown Dog Tick)2 ¶

¶ Tick counts are arithmetic means. Percent effectiveness is based on arithmetic means.

Delivers effective, lasting protection against ticks2

Average duration of efficacy studies against A americanum (Lone Star Tick)2 #

# Tick counts are arithmetic means.
** Three studies were performed and an average duration of efficacy is shown.
†† Tick counts in Study 2 were performed on Day 182.
‡‡ BRAVECTO QUANTUM is not effective against Amblyomma americanum ticks 8 months after dosing.

Onset of efficacy immediately following treatment2

Dermacentor variabilis (American dog tick)
Ixodes scapularis
(black-legged tick)

Rhipicephalus sanguineus
(brown dog tick)

Amblyomma americanum
(lone star tick)

Demonstrated safety of BRAVECTO QUANTUM

BRAVECTO QUANTUM has been safely administered in numerous clinical studies to dogs of various ages, weights, and breeds, including mixed-breeds.2

Safety and comfort

Veterinarians share their insights on the safety and comfort of BRAVECTO QUANTUM for their patients.

Accurate dosing for dogs of any size

Multi-dose vial allows you to draw the exact dose you need for dogs of any size (15 mg fluralaner/kg body weight; 0.1 mL/kg body weight).

Boosting your practice’s efficiency

Learn how BRAVECTO QUANTUM helps optimize your practice—enhancing revenue, streamlining inventory, and simplifying administration.

Help pet owners understand the importance of year-round protection

Bravecto Quantum Pet Owner Checklist Tear Pad US

How to mix BRAVECTO QUANTUM

Watch the video to see how to constitute BRAVECTO QUANTUM prior to administration.

Frequently Asked Questions about BRAVECTO QUANTUM

Safety

WHY IS THE PRODUCT ONLY INDICATED FOR DOGS FROM 6 MONTHS OF AGE?

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Due to the possibility of fast-growing puppies outgrowing the dose, the product was developed for dogs and puppies 6 months of age and older.1

HOW DO I KNOW THAT BRAVECTO QUANTUM IS SAFE FOR MY PATIENTS?

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A margin of safety study was performed and demonstrated safety at doses of 1X (15 mg/kg), 3X (45 mg/kg), and 5X (75 mg/kg) administered every 4 months for a total of 6 doses.2

Concurrent administration

CAN THE PRODUCT BE ADMINISTERED AT THE SAME TIME AS VACCINES?

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In a well-controlled field study, BRAVECTO QUANTUM was used concurrently with other medications, such as vaccines, anthelmintics, antibiotics (including topical), steroids, analgesics, and anesthetics. No adverse reactions were observed from the concurrent use of BRAVECTO QUANTUM with other medications.1

Dosing

WHY IS AN 18 G NEEDLE REQUIRED FOR ADMINISTRATION?

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The formulation is a suspension containing fluralaner powder, and an 18 G needle is required to ensure the suspension is accurately transferred from the vial into the syringe and from the syringe into the patient. Shake the fluralaner powder vial thoroughly.

HOW MUCH VOLUME IS GIVEN PER DOG?

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Dogs should be dosed at 0.1 mL per kg (.045 mL per lb) of body weight. Dogs weighing 10 kg (22 lbs) should be injected with 1.0 mL; dogs weighing 15 kg (33 lbs) should be injected with 1.5 mL, etc.

WHEN CAN DOGS START BRAVECTO QUANTUM?

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Because the efficacy is sustained for an entire year* following administration, dogs can be treated whenever they are unprotected against fleas and ticks. Dogs will not require another dose of flea and tick treatment for 12 months* for the indicated parasites.1

HOW SOON MUST THE PRODUCT BE USED AFTER IT IS MIXED, AND HOW MUST IT BE STORED?

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Before every use, shake the constituted vial vigorously for 30 seconds to achieve a uniform suspension prior to drawing up a dose. The product should be administered within 2 minutes of being drawn into the syringe. Discard vial 3 months after first puncture.

General Product Information

WHY IS ONE VIAL DARK IN COLOR AND THE OTHER IS COLORLESS?

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The sterilization process used for the powder causes the glass to darken in color, which is not the case for the process used to sterilize the liquid vehicle.

WHERE IS THE PRODUCT MANUFACTURED?

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The product is manufactured in Germany.

HOW DO I ORDER THE PRODUCT?

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BRAVECTO QUANTUM is offered directly through the Merck Animal Health online ordering platform, eShop. Please reach out to your Merck Animal Health Outside or Inside Sales Representative to learn how to access the platform.

Resources

Clinic Tools

Download Bravecto clinic tools and in-clinic screens for your veterinary practice.

bravecto-quantum-logo-hero

For technical assistance or to report a suspected adverse drug reaction, contact Merck Animal Health at 1-800-224-5318.

This site is intended for veterinary professionals. Visit our website for pet owners.

*BRAVECTO QUANTUM is indicated to protect against Amblyomma americanum for 8 months.

Important Safety Information

BRAVECTO (fluralaner) Chews for Dogs: The most commonly reported adverse reactions include vomiting, lethargy, diarrhea, anorexia and pruritus. In some cases, adverse events have been reported following use in breeding females. BRAVECTO Chews has not been shown to be effective for 12-weeks’ duration in puppies less than 6 months of age. BRAVECTO Chews is not effective against lone star ticks beyond 8 weeks of dosing. Indicated for dogs 6 months of age and older. BRAVECTO 1-MONTH (fluralaner) Chews: The most commonly reported adverse reactions include itching, diarrhea, vomiting, decreased appetite, elevated ALT, lethargy, and weight loss. Not effective against lone star ticks in puppies less than 6 months of age. Indicated for dogs 8 weeks of age and older. BRAVECTO (fluralaner topical solution) for Dogs: The most commonly reported adverse reactions include vomiting, hair loss, diarrhea, lethargy, decreased appetite, and moist dermatitis/rash. BRAVECTO Topical Solution for Dogs has not been shown to be effective for 12-weeks’ duration in puppies less than 6 months of age. BRAVECTO Topical Solution for Dogs is not effective against lone star ticks beyond 8 weeks of dosing. For topical use only. Avoid oral ingestion. Indicated for dogs 6 months of age and older. BRAVECTO QUANTUM (fluralaner for extended-release injectable suspension) for Dogs: The most commonly reported adverse reactions in a US field study included lethargy, decreased appetite, vomiting, diarrhea, elevated liver enzymes and pruritus. BRAVECTO QUANTUM is not effective against lone star ticks beyond 8 months of dosing. Indicated for dogs 6 months of age and older.
 
BRAVECTO (fluralaner topical solution) for Cats: The most commonly reported adverse reactions include vomiting, itching, diarrhea, hair loss, decreased appetite, lethargy, and scabs/ulcerated lesions. BRAVECTO Topical Solution for Cats is not effective against American dog ticks beyond 8 weeks of dosing. BRAVECTO Topical Solution for Cats has not been shown to be effective for 12-weeks’ duration in kittens less than 6 months of age. The safety of BRAVECTO Topical Solution for Cats have not been established in breeding, pregnant and lactating cats. For topical use only. Avoid oral ingestion. Indicated for cats 6 months of age and older. BRAVECTO PLUS (fluralaner and moxidectin topical solution) for Cats: The most commonly reported adverse reactions include vomiting, hair loss, itching, diarrhea, lethargy, dry skin, elevated ALT, and hypersalivation. BRAVECTO PLUS has not been shown to be effective for 2 months in kittens less than 6 months of age. Use with caution in cats that are heartworm positive. The effectiveness of BRAVECTO PLUS to prevent heartworm disease after bathing or water immersion has not been evaluated. The safety of BRAVECTO PLUS have not been established in breeding, pregnant and lactating cats. Indicated for cats 6 months of age and older.
 
All BRAVECTO products contain fluralaner, which is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. Neurologic adverse reactions have been reported in cats receiving isoxazoline class drugs, even in cats without a history of neurologic disorders. Use with caution in cats with a history of neurologic disorders.

References

  1. BRAVECTO QUANTUM. Product label. Merck Animal Health; 2024.
  2. Freedom of Information Summary, NADA 141-599.