SAFE-GUARD® feed formulations: Deworming meets the pasture.
Parasite protection is now on the menu
SAFE-GUARD feed formulations provide an effective option to deworm cattle without extra handling. Powered by fenbendazole, SAFE-GUARD feed formulations demonstrate the same leading efficacy of other SAFE-GUARD products but with easy administration you can take to the pasture. Choose from a variety of feed options.
SAFE-GUARD®
0.5% Pellets
SAFE-GUARD®
0.5% Top Dress Pellet
SAFE-GUARD®
ENPROAL Molasses Block
SAFE-GUARD®
20% Protein Block
SAFE-GUARD®
1.96% Flaked Meal
SAFE-GUARD®
1.96% Pellets
SAFE-GUARD®
Dewormer Cubes
Meet parasites in the pasture
95% of parasites aren’t living in your herd—they’re living in your pastures.1 One treatment per year is likely not enough to stop reinfection. The SAFE-GUARD Program is a strategic deworming protocol with spring, midsummer and fall treatments to effectively break parasite life cycles and prevent shedding back into the pasture.
Feed formulations make it easy to add a crucial dose during grazing periods.
Time Your Treatment

95% of parasites are in the pasture.
Studies show a 98.7% efficacy rate for all SAFE-GUARD formulations.2
Why feed works
SAFE-GUARD feed formulations offer you the flexibility to deworm your herd without the extra time and labor needed to gather and run them through the chute—all while delivering proven control to help clean up your pasture.
The cumulative dose effect of fenbendazole ensures cattle build up a lethal dose over a few feedings. Free-choice options like blocks (3-day) and mineral (3-to-6-day) use salt as a limiter to help ensure dominant animals step aside after their dose so the rest of the herd can get theirs.
See how much feed you’ll need
Common Questions
How do I know how much to give?
Determining dosage depends on which SAFE-GUARD product you are using. For easy calculations, use our dosage calculator to figure your dose and product needs customized for your herd size. Dosage Calculator.
Is there a product guarantee?
With Safe-Guard, you can expect to see a 90% reduction in fecal egg count aer just 14 days.3 One way you can check it is through a fecal egg count reduction test (FECRT). A FECRT will not only tell you which parasites you’re dealing with but also if they’re responding to your program. Learn more about FECRT.
How do feed formulations kill parasites?
All formulations of SAFE-GUARD are powered by fenbendazole. But with feed formulations, how can you be sure cattle are receiving the proper dose? It’s called the cumulative dose effect. Fenbendazole builds up in the fat tissue of parasites.4 Even cattle that ingest small amounts of SAFE-GUARD over the course of a few feedings will quickly build up to a dose that is lethal to internal parasites.
How do I know feed formulations will work?
A comprehensive set of 12 studies have demonstrated that SAFE-GUARD blocks, cubes, pellets and free-choice mineral are effective at keeping cattle clean:
- 12 studies show higher than 91% efficacy for Safe-Guard feed formulations 5-16
- 6 studies show an average extra gain of 40 lbs. in stocker cattle 17-22
- 4 studies show an average weaning weight increase of 31 lbs 18, 23-25
- 4 studies show a 16% increase in average daily gain 6, 20, 21, 26
What worms does SAFE-GUARD kill?
SAFE-GUARD offers broad-spectrum control for a variety of parasites.
| BANKRUPT WORM (T. colubriformis) | Adult ● L4 |
| BARBER’S POLE WORM (Haemonchus spp.) | Adult ● L4 |
| BROWN STOMACH WORM (Ostertagia ostertagi) | Adult |
| HOOKWORM (Bunostomum phlebotomum) | Adult ● L4 |
| LUNGWORM (Dictyocaulus viviparus) | Adult |
| NODULAR WORMS (Oesophagostomum radiatum) | Adult ● L4 |
| SMALL INTESTINE WORM (Cooperia punctata, C. oncophora) | Adult ● L4 |
| SMALL STOMACH WORM (Trichostrongylus axei) | Adult ● L4 |
| THREAD-NECKED WORM (Onchocerca cervicalis) | Adult ● L4 |
How can I test my current deworming protocol?
The Fecal Egg Count Reduction Test, or FECRT, is a standardized diagnostic tool to determine if there is potential parasite resistance with your current dewormer. After deworming, you should see a 90%+ reduction in fecal egg count. If these results are not achieved, the reason why should be investigated with a veterinarian to determine if improper dosing and/or resistance has affected the outcome. It’s a great way to learn which parasites you are dealing with and if they are responding to your program. Learn more about FECRT.
Why does SAFE-GUARD use fenbendazole?
Parasites can’t excrete fenbendazole. This means even cattle that ingest small amounts of SAFE-GUARD feed products over the course of a few feedings quickly build up a lethal dose for any parasites that may be present.
Take the fight against parasites to your pastures with SAFE-GUARD feed formulations
Important Safety Information
Do not use in beef calves less than 2 months old, dairy calves and veal calves. A withdrawal period has not been established for this product in pre-ruminating calves. Additionally, the following meat withdrawal and milk discard times apply:
Safe-Guard Paste: Cattle must not be slaughtered for 8 days. For dairy cattle, the milk discard time is 96 hours.
Safe-Guard Suspension: Cattle must not be slaughtered for 8 days. For dairy cattle, the milk discard time is 48 hours.
Safe-Guard EnProAl Type C Medicated Block: Cattle must not be slaughtered for 11 days. For use in beef cattle only.
Safe-Guard 20% Protein Type C Medicated Block: Cattle must not be slaughtered for 16 days. For use in beef cattle only.
Safe-Guard Type A and other medicated feed products (pellets, cubes, free-choice mineral, or free-choice liquid): Cattle must not be slaughtered for 13 days. For dairy cattle, the milk discard time is 60 hours.
References
- Herd, R. Strategies for Nematode Control in Cattle. Modern Veterinary Practice, 1985.
- Merck Animal Health National FECRT Database.
- Coles, et. al. WAAVP methods for the detection of anthelmintic resistance in nematodes of veterinary importance.
- Vercruysse J, Claerebout E. Mechanisms of actions of anthelmintics. Merck Veterinary Manual Online. https://www.merckvetmanual.com/pharmacology/anthelmintics/mechanisms-of-action-of-anthelmintics. Accessed February 2, 2021.
- Intervet Safeguard Technical Bulletin Part Number A640416. 2001.
- Hoechst-Roussel Agri-Vet Company Study Number A640468.
- Blagburn BL, et al. Ecacy of fenbendazole medicated feed blocks against gastrointestinal nematode infections in calves. Am J Vet Res. 1987;48(6):1017-1019.
- Blagburn BL, et al. Evaluation of three formulations of fenbendazole (10% suspension, .5% pellets and 20% premix) against nematode infections in cattle. Am J Vet Res. 1986;47(3):834-836.
- Saad MB, et al. Ecacy of Fenbendazole against adult Dictyocaulus viviparus in experimentally infected calves. Am J Vet Res. 1977;38(9):1427-1428.
- Crowley JW, et al. Further controlled evaluations of fenbendazole as a bovine anthelmentic. Am J Vet Res. 1977;38(5):689-692.
- Bliss DH. Comparative evaluation of fenbendazole (5mg/kg) administered either via a free-choice mineral or in a 10% oral suspension and ivermectin (100 or 200 mcg/kg) administered subcutaneous.
- Miller JE. Ecacy of Safeguard En-Pro-Al molasses deworming supplement blocks against inhibited larvae of Ostertagia ostertagia. Southern Conference on Animal Parasites. 1989. March 26-28. Abstract #75.
- HRVET Study No 97-0020.
- Smith SJ, et al. Effects of Safeguard free choice protein blocks on trichostrongyle nematodes in pastured cattle from eastern South Dakota. Proc. South Dakota Academy of Science. 2012;91.
- Williams JC, et al. Ecacy of a spring fenbendazole treatment program to reduce numbers of Ostertagia ostertagi inhibited larvae in beef stocker cattle. Vet Parasitol. 1995;59(2):127-137.
- Reinemeyer CR, et al. Larvicidal ecacy of three formulations of fenbendazole against experimentally-induced gastrointestinal nematode infections in cattle. Intervet Research Report.
- Smith RA, et al. Pasture deworming and (or) subsequent feedlot deworming with fenbendazole. I. Effects on grazing performance, feedlot performance and carcass traits of yearling steers. Bov Pract. 2000;34(2):104-114.
- Taylor FT. Effects of a strategic deworming program in beef cattle with subclinical parasitism in the western United States. BCVA Edinburgh. 1996.
- Rowland W, et al. Effects of strategic deworming with Safeguard, Gainpro supplementation and (or) implantation with Revalor-G on grazing performance of stocker steers. 2000.
- Hoechst-Roussel Agri-Vet Company Study Number A640438.
- Hoechst-Roussel Agri-Vet Company Study Number A640039.
- Miller JE, et al. Effect of fenbendazole molasses supplement block treatment on nematode infection and subsequent weight gain of weanling beef calves. Vet Parasitol. 1992;44(3-4):329-337.
- Kvasnicka WG, et al. Fenbendazole in a strategic deworming program. The Compendium. Food Animal Parasitology. 1996;18(4):113-117.
- Wholgemuth KM, et al. Deworming beef cow and calves with fenbendazole: effect on weaning weight of calves. North Dakota Farm Research Bimonthly Bulletin. 1990;48(4):27-30.
- HRVET Study GHM/19. Cow/calf producers in the northern plains have wondered if parasite control can pay for itself. 1990.
- Keith EA. Utilizing feed grade formulations of fenbendazole for cattle. Agri-Practice. 1992;13(1):17.
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