Canine Adenovirus Type 2

Disease Overview

Canine adenovirus type 2 (CAV-2) is related to the hepatitis virus, canine adenovirus type 1 (CAV-1). CAV-2 is used in vaccines to provide protection against canine infectious hepatitis. CAV-2 is also one of the causes of infectious tracheobronchitis, also known as canine cough. ³⁰

Merck Animal Health Solutions

NOBIVAC® Canine 1-DAPPv

NOBIVAC® Canine 1-DAPPv+Cv

Nobivac® Canine 1-DAPPvL₂+Cv

NOBIVAC® Canine 1-DAPPv+L₄

Nobivac® Canine 3-DAPv

NOBIVAC® Intra-Trac®₃

NOBIVAC® Intra-Trac®₃ ADT

Transmission

Adenoviruses are spread directly from dog to dog through infected respiratory secretions or by contact with contaminated feces or urine.

Clinical Signs³⁰

Respiratory disease (CAV-2)

Dry, hacking cough (dogs)
Retching
Sneezing
Watery nasal discharge
Pneumonia, inappetence, fever, and lethargy in severe cases

Hepatitis (CAV-1)

Fever
Abdominal pain
Vomiting
Diarrhea

Risk Factors

Dogs that come from shelters, rescue centers, breeding kennels, or pet stores
Boarding at a kennel or doggie daycare
Visiting groomers, dog parks, or engaging with other dogs on a daily basis
Dogs that live in multi-pet homes

References

Greene C. Infectious canine hepatitis and canine acidophil cell hepatitis. In: Greene CE, ed. Infectious Diseases of the Dog and Cat. 3rd ed. St. Louis, MO: Saunders/Elsevier; 2006:43.