The new look of protection.

All cattle vaccines from Merck Animal Health now live under the BOVILIS name. They’re the same vaccines you’ve relied on for years – only with updated names and packaging. Each product has its own distinct color and is clearly marked, making it easy to ensure you’re selecting the right vaccine at the right time.

The first and only intranasal vaccine with viral and bacterial pneumonia protection.

That means protection against IBR, BRSV, PI3, Pasteurella multocida and Mannheimia haemolytica. BOVILIS NASALGEN 3-PMH is also safe to use in calves 1 week of age or older for a strong, healthy foundation. And a unique BluShadow™ diluent means there’s no second-guessing which animals have been vaccinated.

Gain More with BOVILIS VISION.

BOVILIS VISION vaccines give cattle strong protection against clostridial disease. Each is powered by the proprietary SPUR adjuvant that boosts vaccine performance while causing fewer reactions and reducing stress on cattle post-vaccination.1-3 This also leads to better feed conversion and increased weaning weights when compared to conventional clostridial vaccines.4-7

Stop pinkeye before it starts.

For broad protection, choose a combination approach to vaccination. 

Bovilis® Piliguard® vaccines and Bovilis® 20/20 Vision® 7 protect against Moraxella bovis, a major cause of pinkeye. However, a recent study found up to 80% of cases include Moraxella bovoculi alone, or along with M. bovis.8 Utilizing Moraxella Bovoculi Bacterin to protect against M. bovoculi, along with your other pinkeye solutions, can help ensure maximum protection.

From the ranch to the feedyard, preconditioning improves performance.
With the right PrimeVAC program, you can give your cattle the marketing edge they need so you get the payday you deserve.

Learn about the different programs below.
Then talk to your Merck Animal Health representative to get started.

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See more available vaccine options in the BOVILIS portfolio from Merck Animal Health.

Browse the complete BOVILIS vaccine lineup below.

Respiratory

Respiratory diseases are the most common and costly infections plaguing the North American cattle industry.10,11

Cattle vaccines from Merck Animal Health are designed to protect your herd and profits.

Intranasal vaccine shown to be effective for the vaccination of healthy cattle 1 week of age or older against infectious Bovine Rhinotracheitis (IBR) virus, Bovine Respiratory Syncytial Virus (BRSV), Parainfluenza 3 virus, Mannheimia haemolytica and Pasteurella multocida.

Intranasal vaccine shown to be effective for the vaccination of healthy cattle 1 week of age or older against infectious Bovine Rhinotracheitis (IBR) virus, Bovine Respiratory Syncytial Virus (BRSV) and Parainfluenza 3 virus.

Intranasal vaccine shown to be effective for the vaccination of healthy cattle 5 months of age or older against disease caused by IBR and PI3 virus.

Shown to be effective for the vaccination of healthy cattle 3 months of age or older against disease caused by Pasteurella multocida and Mannheimia haemolytica.

Intranasal vaccine shown to be effective for the vaccination of healthy cattle 1 week of age or older against Mannheimia haemolytica and Pasteurella multocida.

Shown to be effective for the vaccination of healthy cattle 3 months of age or older against respiratory disease and abortion due to infectious bovine rhinotracheitis (IBR), respiratory disease and fetal infection, including persistently infected calves due to bovine virus diarrhea virus (BVD) Types 1 and 2, bovine respiratory syncytial virus (BRSV) and parainfluenza3 virus (PI3). Respiratory and reproductive efficacy and duration of immunity has been demonstrated against disease caused by the BVD Type 1b strain.

Shown to be effective for the vaccination of healthy cattle 3 months of age or older against respiratory disease and fetal infection, including persistently infected calves caused by bovine diarrhea virus (BVD) Types 1 & 2. Respiratory and reproductive efficacy and duration of immunity has been demonstrated against disease caused by the BVD Type 1b strain.

Shown to be effective for the vaccination of healthy cattle 3 months of age or older against respiratory disease and abortion due to infectious bovine rhinotracheitis (IBR), respiratory disease and fetal infection, including persistently infected calves due to bovine virus diarrhea virus (BVD) Types 1 and 2, bovine respiratory syncytial virus (BRSV), parainfluenza3 virus (PI3), Mannheimia Haemolytica and Pasteurella multocida. Respiratory duration of immunity has been shown to be at least 1 year for IBR and BVD (Types 1 and 2) and at least 16 weeks for Mannheimia haemolytica and Pasteurella multocida. Reproductive duration of immunity has been shown to be at least 217 days for IBR and at least 206 days for BVD (Types 1 and 2). Duration of immunity for BRSV and PI3 has not been established.Respiratory and reproductive efficacy and duration of immunity has been demonstrated against disease caused by the BVD Type 1b strain.

Clostridial (Black Leg)

Naturally found in soil and the intestines of cattle, clostridial organisms can cause unexpected mortality to a herd in the form of blackleg and other fatal diseases. Protect your herd’s health and your profits with vaccines from Merck Animal Health.

Shown to be effective for the vaccination of healthy cattle and sheep against disease caused by Clostridium chauvoei (Blackleg), Cl. Septicum (Malignant edema), Cl. novyi (Black disease), Cl. sordellii, Cl. perfringens Types C and D (Enterotoxemia).

Shown to be effective for the vaccination of healthy cattle against disease caused by Clostridium chauvoei (Blackleg), Cl. septicum (Malignant edema), Cl. novyi (Black disease), Cl. sordellii, Cl. perfringens Types C and D (Enterotoxemia), and Histophilus somni.

Shown to be effective for the vaccination of healthy cattle and sheep against disease caused by Clostridium chauvoei (Blackleg), Cl. septicum (Malignant edema), Cl. haemolyticum (Bacilliary Hemoglobinuria (Red water), Cl. novyi (Black disease), Cl. sordellii and Cl. perfringens Types C and D (Enterotoxemia).

Shown to be effective for the vaccination of healthy cattle against disease caused by Clostridium chauvoei, Cl. septicum, Cl. haemolyticum, Cl. novyi, Cl. sordellii, Cl. perfringens Type C and D, and Histophilus somni.

Show to be effective for the vaccination of healthy cattle, sheep and goats against Enterotoxemia caused by Clostridium perfringens Types C & D.

Shown to be effective for the vaccination of healthy cattle, sheep and goats against disease caused by Clostridium perfringens Types C and D (Enterotoxemia) and Cl. tetani (Tetanus).

Shown to be effective for the vaccination of healthy cattle 3 months of age or older against disease caused by Clostridium chauvoei, Cl. septicum, Cl. novyi Type B, Cl. haemolyticum, Cl. sordellii, Cl. tetani and Cl. perfringens Types C and D.

Shown to be effective for the vaccination of healthy cattle and sheep against disease caused by Clostridium chauvoei, C. septicum, C. novyi Type B, C. haemolyticum (known also as C. novyi Type D), C. tetani and C. perfringens Types C and D.

Reproductive

Breeding stock and their offspring are critical to the success of your operation. Protect both with the reproductive lineup of vaccines from Merck Animal Health.

Shown to be effective for the vaccination of healthy cattle 6 months of age or older against L. canicola, L. grippotyphosa, L. hardjo including L. borgpetersenii serovar hardjo bovis, L. icterohaemorrhagiae, and L. pomona. Effective against urinary shedding of hardjo bovis organisms.

Shown effective for the vaccination of healthy cattle 6 months of age or older against respiratory disease and abortion due to infectious bovine rhinotracheitis (IBR), respiratory disease and fetal infection, including persistently infected calves due to bovine virus diarrhea virus (BVD) Types 1 & 2, bovine respiratory syncytial virus (BRSV) and
parainfluenza3 virus (PI3) and leptospirosis (caused by Leptospira canicola, L. grippotyphosa,
L. hardjo
– including the L. borgpetersenii serovar hardjo bovis, L. icterohaemorrhagiae, and L. pomona). Effective against urinary shedding of hardjo bovis organisms. Respiratory and reproductive efficacy and duration of immunity has been demonstrated against disease caused by the BVD Type 1b strain.

Shown effective for the vaccination of healthy cattle 6 months of age or older against respiratory disease and abortion due to infectious bovine rhinotracheitis (IBR), respiratory disease and fetal infection, including persistently infected calves due to bovine virus diarrhea virus (BVD) Types 1 & 2, bovine respiratory syncytial virus (BRSV) and
parainfluenza3 virus (PI3), reproductive disease caused by Campylobacter fetus and leptospirosis (caused by Leptospira canicola, L. grippotyphosa, L. hardjo – including the L. borgpetersenii serovar hardjo bovis, L. icterohaemorrhagiae, and L. pomona). Effective against urinary shedding of hardjo bovis organisms. Respiratory and reproductive efficacy and duration of immunity has been demonstrated against disease caused by the BVD Type 1b strain.

Shown to be effective for the vaccination of healthy cattle against L. canicola, L. grippotyphosa, L. hardjo including L. borgpetersenii serovar hardjo bovis, L. icterohaemorrhagiae, and L. pomona and reproductive disease caused by Campylobacter fetus. Effective against urinary shedding of hardjo bovis organisms.

Mastitis

Your cows’ production and your operation’s profitability take a direct hit if coliform mastitis takes hold. Vaccinate before it impacts your milk string.

Shown to be effective for the vaccination of healthy dairy cattle against mastitis caused by E. coli – Lowest level of endotoxins help minimize potential side effects.¹²⁻¹³

Scours

Calf scours – neonatal diarrhea – exerts a costly toll on the livestock industry. While the bacteria, viruses and parasites that cause the disease are a part of livestock production, scours can be prevented. For exceptional protection, turn to vaccines from Merck Animal Health.

Multiple-antigen product shown to be effective for the vaccination of healthy pregnant cattle to provide passive immunity against neonatal calf diarrhea caused by enterotoxigenic E. coli pilus type K99, bovine Group A Serotype G6 rotaviruses, bovine coronavirus, and enterotoxemia caused by Cl. perfringens Types C and D.

Intranasal vaccine shown to be effective for the vaccination of healthy calves against enteric disease caused by bovine coronavirus. Efficacy shown in calves 3 days of age and older. Safety has been shown in calves 1 day of age and older.

Pinkeye

Spread by flies, pinkeye causes pain, stress and weight loss in cattle. If your cattle go blind or develop clouded eyes, your operation’s profitability will take an additional hit. Prevent pinkeye before it blindsides your ROI.

Shown to be effective for the vaccination of healthy cattle against disease caused by Clostridium chauvoei (Blackleg), Cl. septicum (Malignant edema), Cl.novyi (Black disease), Cl. sordellii and Cl. perfringens Types C and D (Enterotoxemia) and Moraxella bovis (Pinkeye or infectious bovine keratoconjunctivitis).

Shown to be effective for the vaccination of healthy cattle 14 weeks of age or older against pinkeye (infectious bovine keratoconjunctivitis) caused by Moraxella bovoculi.

A cell-free Moraxella bovis bacterin shown effective for the vaccination of healthy cattle against Moraxella bovis.


1FTR 92-3 Vision 8 Injection Site Blemish Study.

2FTR 96-2 Analysis of Post-Vaccinal Injection Sites Using Ultrasound.

3FTR 96-4 Evaluation of Injection Site Blemishes Using Ultrasonography Following Administration of Two Commercial Multivalent Clostridial Vaccines.

4Technical Services Field Trial Report 93-9. 1993. Weaning weight comparison of Vision 7 and Ultrabac 7 in a Wyoming beef herd.

5Technical Services Field Trial Report 93-14. 1993. Vision Weaning Weight Trials.

6Veterinary Services Field Trial Report 93-15. 1993. Weight comparison at weaning in 5 beef herds comparing Vision (2 mL) to 5 mL 7-way administered at spring branding.

7Veterinary Services Field Trial Report 96-5. 1996. Weaning weight comparison of calves vaccinated with Vision 8 vaccine or a 5 mL 8-way clostridial vaccine.

8Pinkeye in cattle. Mississippi State University Extension Service. POD-02-14.

9Clarke R. November 2014. The full cost of pinkeye in cattle. Canadian Cattlemen website. November 2014. https://www.canadiancattlemen.ca/features/the-full-cost-of-pink-eye-in-cattle/. Accessed May 12, 2021.

10Fulton RW. Bovine respiratory disease research (1983–2009). Cambridge University Press. Anim Health Res Rev. 2009;10(2):131–139.

11Irsik M, Langemeier M, Schroeder T, Spire M, Roder JD. Estimating the Effects of Animal Health on the Performance of Feedlot Cattle. Bov Pract. 2006;40(2):65-74.

12 Comparison of endotoxin concentrations in BOVILIS® J-5 with those in three commercially available Gram-negative, lipopolysaccharide core-antigen vaccines, Merck Animal Health technical bulletin, 2020.

13Brito LA, Singh M. Acceptable levels of endotoxin in vaccine formulations during preclinical research. J Pharm Sci. 2011;100:34-37.

See more solutions that can help improve herd health and boost performance for cow-calf and stocker operations.

An effective deworming program can help you make the most of your vaccination protocol.

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