
Extended-duration protection fleas, ticks, and heartworms with 2X the duration of monthly products.*



Features and benefits of 2 months’ protection with BRAVECTO® PLUS

Trusted active ingredient
- Fluralaner, an ectoparasiticide belonging to the isoxazoline group
- Kills fleas, ticks, roundworms, hookworms, and prevents heartworm disease for 2 months

Persistent, long-lasting coverage
- Rapid onset of action and speed of kill
- 2-month duration reduces gaps in protection that can result from missed doses of monthly products

Convenient, topical parasite protection
- Helps improve pet owner compliance
- Available by veterinary prescription only
Indications
BRAVECTO PLUS is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment of infections with intestinal roundworm (Toxocara cati; 4th stage larvae, immature adults and adults) and hookworm (Ancylostoma tubaeforme; 4th stage larvae, immature adults and adults). BRAVECTO PLUS kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick) and Dermacentor variabilis (American dog tick) and Haemaphysalis longicornis (Asian longhorned tick)] for 2 months in cats and kittens 6 months of age and older and weighing 2.6 lbs or greater.

Prescribe BRAVECTO PLUS depending on the patient’s weight1
One application per weight

†Cats over 27.5 pounds should be administered the appropriate combination of tubes
BRAVECTO PLUS: All-in-one flea, tick, and heartworm treatment for cats
Specifically designed for the challenges of treating cats, BRAVECTO PLUS (fluralaner and moxidectin topical solution) for Cats protects against fleas, ticks, heartworms, and intestinal parasites in one easy dose. BRAVECTO PLUS delivers double the duration of protection compared with monthly products.
Superior flea, tick, and heartworm control for cats
Provide the comprehensive protection against fleas, ticks, heartworms, and intestinal parasites that your patients need. Not only does BRAVECTO PLUS protect against a broad range of parasites, it also delivers 2X the duration of protection compared with monthly combination products.1*

2X the duration of monthly products*
Recommend the feline flea, tick, and heartworm topical that is indicated for internal and external parasites and lasts 2 months.

Extended duration = long-lasting protection against fleas
The 2-month efficacy of a single dose of BRAVECTO PLUS against Ctenocephalides felis fleas has been confirmed in laboratory studies.1
Residual speed of kill and persistent efficacy against fleas (C Felis)1

Efficacy against fleas was 100% within 12 hours and >99% for 2 months.1
Extended duration = long-lasting protection against ticks
Efficacy against ticks was 100% for 1 month and >99% for 2 months.2
Efficacy against ticks (Ixodes Scapularis and Dermacentor Variabilis)2

Tick Count
Broad spectrum = prevents heartworm disease
BRAVECTO PLUS was 100% effective against heartworm disease for 2 months. Uniquely, in the studies the cats were treated 60 days before 3rd stage larval infection, thereby proactively protecting the cats.3
Innovative approach to heartworm (Dirofilaria Immitis) disease prevention3

Broad spectrum = treatment of roundworms
Efficacy against roundworms (Toxocara Cati)4

Nematode Life Stage
Broad spectrum = treatment of hookworms
In well-controlled laboratory studies, BRAVECTO PLUS was effective against naturally and experimentally induced adult and experimentally induced 4th stage larval and immature adult Ancylostoma tubaeforme infection in cats.5
Efficacy against hookworms (Ancylostoma tubaeforme)5

Nematode Life Stage
BRAVECTO PLUS benefits cat owners and your clinic

Creates less stress
Long-lasting protection reduces stress by offering continuous flea, tick, and heartworm treatment for cats, ensuring peace of mind for pet owners and less stress on cats.
Fits scientific recommendations
The Companion Animal Parasite Council (CAPC) recommends year-round protection for cats against fleas, ticks, heartworms, roundworms, and hookworms.6-9
Easy for cat owners
Use of an extended-duration product like BRAVECTO PLUS makes it easier for clients to achieve continuous coverage compared with 12 monthly doses.
Supporting published studies:
In addition to the studies supporting the efficacy and safety of BRAVECTO PLUS, our BRAVECTO portfolio of published studies can be found at Parasites & Vectors in the BRAVECTO collection.


Learn more about extended-duration, broad-spectrum flea, tick, and heartworm treatment for cats
Contact us for more information about BRAVECTO PLUS for your hospital.
We can answer all your questions and get you started prescribing BRAVECTO PLUS for the felines in your care.
Frequently Asked Questions about BRAVECTO PLUS for Cats
Yes, it’s important to provide year-round flea, tick, and heartworm protection for cats. Talking with pet owners about extended-duration protection can help increase their compliance and ensure patients are protected all year long. With BRAVECTO PLUS, you can offer twice the duration of monthly products, leading to fewer gaps in protection.
Providing convenient solution to pet owners helps improve compliance, and with BRAVECTO PLUS, one dose protects cats from fleas, ticks, heartworms, AND intestinal parasites for 2 months.
In a well-controlled field study, BRAVECTO PLUS was used concurrently with other medications, such as vaccines, anthelmintics, antibiotics, and steroids. No adverse reactions were observed from the concurrent use of BRAVECTO PLUS with other medications.1

For technical assistance or to report a suspected adverse drug reaction, contact Merck Animal Health at 1-800-224-5318.
This site is intended for veterinary professionals. Visit our website for pet owners.
*BRAVECTO PLUS is indicated for 2 months in cats and kittens 6 months of age and older, and weighing 2.6 pounds or greater.
Important Safety Information
BRAVECTO (fluralaner topical solution) for Cats: The most commonly reported adverse reactions include vomiting, itching, diarrhea, hair loss, decreased appetite, lethargy, and scabs/ulcerated lesions. BRAVECTO Topical Solution for Cats is not effective against American dog ticks beyond 8 weeks of dosing. BRAVECTO PLUS (fluralaner and moxidectin topical solution) for Cats: The most commonly reported adverse reactions include vomiting, hair loss, itching, diarrhea, lethargy, dry skin, elevated ALT, and hypersalivation. BRAVECTO PLUS has not been shown to be effective for 2 months in kittens less than 6 months of age. Use with caution in cats that are heartworm positive. The effectiveness of BRAVECTO PLUS to prevent heartworm disease after bathing or water immersion has not been evaluated.
BRAVECTO Topical Solution for Cats and BRAVECTO PLUS for Cats are for topical use only. Avoid oral ingestion. The safety of BRAVECTO Topical Solution for Cats and BRAVECTO PLUS have not been established in breeding, pregnant, and lactating cats.
All BRAVECTO products contain fluralaner, which is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Neurologic adverse reactions have been reported in cats receiving isoxazoline class drugs, even in cats without a history of neurologic disorders. Use with caution in cats with a history of neurologic disorders.
References
- BRAVECTO® PLUS. Product label. Merck Animal Health; 2022.
- BRAVECTO® PLUS Freedom of Information Summary, NADA 141-518. (Studies S15312-03, 15311-01). November 14, 2019. Accessed February 12, 2025
- BRAVECTO® PLUS Freedom of Information Summary, NADA 141-518. (Studies S15102-01, S15102-03). November 14, 2019. Accessed February 12, 2025
- BRAVECTO® PLUS Freedom of Information Summary, NADA 141-518. (Studies S15356-00, S15187-00). November 14, 2019. Accessed February 12, 2025
- BRAVECTO® PLUS Freedom of Information Summary, NADA 141-518. (Studies S15138-00, S15355-00). November 14, 2019. Accessed February 12, 2025
- Ticks. Companion Animal Parasite Council. Updated April 7, 2023. Accessed January 22, 2024. https://capcvet.org/guidelines/ticks/
- Fleas. Companion Animal Parasite Council. Updated September 19, 2017. Accessed January 22, 2024. https://capcvet.org/guidelines/fleas/
- Ascarid. Companion Animal Parasite Council. Updated September 12, 2022. Accessed January 22, 2024. https://capcvet.org/guidelines/ascarid/
- Hookworms. Companion Animal Parasite Council. Updated September 12, 2022. Accessed January 22, 2024. https://capcvet.org/guidelines/hookworms/
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