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PROTECTION FOR DOGS FACING THE MOST SEVERE CHALLENGES21 No dogs vaccinated with Nobivac® Canine 1-DAPPv+L₄ died or required euthanasia 54% mortality and euthanasia in control groups, reflecting the severity of challenge Clinical efficacy results showed that Nobivac® Canine 1-DAPPv+L₄ also prevented1 Leptospiremia More than 85% of vaccinates had no leptospiremia; leptospires were cleared quickly from the blood […]

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PREVENT URINARY SHEDDING OF LEPTOSPIRES22 A key objective of vaccination is to prevent urinary shedding of leptospires, which has potential zoonotic risk:22,23 0% of dogs vaccinated with Nobivac® Canine 1-DAPPv+L4 developed leptospiruria All of the control dogs challenged with L. canicola and L. grippotyphosa, 80% of control dogs challenged with L. icterohaemorrhagiae, and 50% of control dogs challenged with L. pomona developed […]

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