Bursal Disease Vaccine

This vaccine contains an intermediate strain of Infectious Bursal Disease (IBD) Virus propagated in SPF (Specific Pathogen Free) substrates. This strain was developed from a bursal disease field isolate.

This product has been shown to be effective for the vaccination of healthy chickens 1 day of age or 2 weeks of age or older against infectious bursal disease.

  • D-78 strain of IBD virus is derived from a natural field strain; it has not been attenuated by tissue culture used as directed or egg passage
  • Capable of overcoming moderate levels of maternal antibody to induce strong, early protection
  • Produces minimal damage to the bursa
  • Safe to use in chickens at 1 day of age
  • Induces the strongest antibody response of any standard strain intermediate IBD vaccine
  • Protects the lymphoid system
  • Cloned to ensure consistent protection from serial to serial

  • Infectious Bursal disease (IBD)

Many factors must be considered in determining the vaccination program for a particular farm or poultry operation. To be fully effective, the vaccine must be administered to healthy receptive birds held in proper environment under good management. In addition, the response may be modified by the age of the birds and their immune status. Seldom does 1 vaccination under field conditions produce complete protection for all individuals in a given flock. The amount of protection required will vary with the type of operation and the degree of exposure that a flock is likely to encounter.


  1. Do not use any disinfectants in the drinking water for 48 hours before vaccinating and 24 hours after vaccination.
  2. Withhold water from the chickens until they are thirsty.
  3. Calculate the water volume needed so the vaccine will be consumed in approximately 2 hours.
  4. Optional: as an aid in preserving the virus, add a vaccine stabilizer to the stock solution or to the tank containing clean, cool, non-chlorinated water. Agitate thoroughly. Follow the manufacturer’s rate of administration and wait time.
  5. Add rehydrated vaccine from vial to the water and mix thoroughly.
  6. Turn on tank valve or automatic dosing system.
  7. Provide as sole source of drinking water until all vaccine-water solution has been consumed.

Calculate the water volume needed. For example, a machine which dispenses 21 ml to a box of 100 chickens – total volume for 1,000 doses is 210 ml of non-chlorinated water. For coarse spray in chicken houses, follow manufacturer’s direction for the particular spray machine. Add rehydrated vaccine and mix thoroughly.

10 x 10,000 dose ampules

  2. All chickens should be vaccinated at the same time.
  3. Use entire contents when first opened.
  4. Do not vaccinate within 21 days before slaughter.
  5. Store at 2° to 8° C (35° to 46° F).
  6. Inactivate unused contents before disposal.
  7. Do not mix with other products, except as specified on this label.
  8. In case of human exposure, contact a physician.
  9. Contains gentamicin as a preservative.

This vaccine has undergone rigid potency, safety and purity tests, and meets Merck Animal Health, U.S. and local regulatory requirements. It is designed to stimulate effective immunity when used as directed, but the user must be advised that the response to the product depends upon many factors, including, but not limited to, conditions of storage and handling by the user, administration of the vaccine, health and responsiveness of the individual chickens, and the degree of field exposure. A safety data sheet (SDS) is available upon request. This and any other consumer information can be obtained by calling Merck Animal Health Customer Service at 1-800-211-3573.

Keep a record of vaccine, quantity, serial number, expiration date, and place of purchase; the date and time of vaccination; the number, age, breed, and locations of chickens; names of operators performing the vaccination and any observed reactions.

Contact our sales or technical services representatives to help design a custom vaccination program.

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For additional information, please see the product label.
For more information regarding efficacy and safety data, go to

*Data on file, Merck Animal Health

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