Parasite control is an ongoing battle. SAFE-GUARD (fenbendazole) is ready.

When it comes to deworming cattle, choose SAFE-GUARD to help get the most from your herd. SAFE-GUARD features broad-spectrum protection against the most concerning internal parasites, including OstertagiaCooperia and more.

Deworming cattle to stay ahead of profit-eating parasites.

The signs of a severe parasite infection are easy to spot. But it’s important to keep an eye out for the less severe signs that can indicate the start of a problem, so you can take swift action.


Reduced feed intake

Increased incidence of disease

Decreased reproductive performance

Lower milk production

SAFE-GUARD is a fast-acting dewormer that goes straight to the gut, killing worms where they live.

Keep cattle protected in the pasture.

Parasites shed by cattle last season are often the source of infection for cattle this season. Cleaning up your pasture starts with deworming cattle to remove worms and stop egg shedding back onto the grass.


  1. Cattle ingest infective larvae (L3)
  2. Immature worms move to the gut where they mature; adult worms lay eggs
  3. Eggs pass through feces back onto the grass where they become larvae and continue to mature (L1, L2)
  4. Infective larvae (L3) are mobile and move away from manure pats to grass to be consumed

Deworming cattle without reworking cattle.

SAFE-GUARD is the only dewormer available in feed formulations that can be added directly to feeders or administered in the pasture for convenient deworming between spring and fall treatments. It builds up bite-by-bite, so even cattle that ingest small amounts over a few feedings still quickly build to a dose that is lethal to internal parasites.

A veterinarian’s take.

Parasites can significantly weigh down your herd. Louisiana veterinarian Dr. Paul Whittington explains how they impact animal health and performance.

Fighting resistance by doubling down.

Parasites can significantly weigh down your herd. Louisiana veterinarian Dr. Paul Whittington explains how they impact animal health and performance.

Deworming Cattle: Schedule and Time Matter

When it comes to deworming cattle, schedule based on your operation type and location, as well as the parasite life cycle. Doing so reduces the parasite burden both in your herd and on the pasture.

Select your operation type to see the recommended guidelines.



Deworm at the end of the grazing season or after the first killing frost in areas where cattle remain on-pasture year-round.


  • If fall treatment was not given after the first frost, deworm at turnout or grass green-up – and then again 6-8 weeks later.
  • If fall treatment was given after the first frost, deworm the adult cow and her suckling calf 6-8 weeks after spring grazing begins.


In warm weather regions, a second deworming given 6-8 weeks after the first spring deworming may be warranted due to high parasite populations and transmission.




  • Deworm cattle at turnout, or the beginning of extended grass growth.
  • Follow with a second treatment 3-4 weeks later.
  • Finish with a third treatment three to four weeks after the second deworming.


  • A deworming treatment at turnout can help provide control for the winter grazing season.
  • A second treatment three to four weeks later is recommended if there was a possibility of pasture contamination at turnout.




Dairy cows exposed to moderate or high levels of parasites or grazing pastures should receive treatment at freshening and again after 6 weeks.


Dairy cows exposed to low levels of parasites only need to be treated at freshening or as a herd once a year, ideally in late fall.


  • Transition cows have different energy needs from other cows in the milking rotation.
  • Treating in the first transition period will reduce internal parasite loads.
  • The key is to deworm the “group” on a specific day, on a regular schedule.


Nail the timing of your treatments with
SAFE-GUARD’s simple scheduling tool.

Determine how much of your preferred
formulation you’ll need to effectively treat your
herd with the SAFE-GUARD dosage calculator.


SAFE-GUARD Paste and Suspension: cattle must not be slaughtered within 8 days following last treatment; Mineral and medicated feed products: 13 days; EN-PRO-AL Molasses Block: 11 days; Protein Block: 16 days; For dairy cattle, the milk discard time is zero hours. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal. For complete information, refer to the product label.