Bursal Disease – Marek’s Disease – Newcastle Disease Vaccine

INNOVAX-ND-IBD provides life-long protection against infectious bursal disease, Newcastle disease and Marek’s disease in one easy-to-administer dose.

This vaccine has been shown to be effective for the vaccination of healthy 18 day-old chicken embryos or one-day-old chickens against Marek’s disease, Newcastle disease, standard and variant infectious bursal disease.

  • Unique 3-in-1 protection
  • Life-long disease prevention
  • Early immune response
  • More efficient disease control
  • Provides protection for virulent ND, IBD and Marek’s disease
  • Offers effective protection in the face of ND virus maternal antibodies
  • Replaces a conventional live ND vaccination program in the absence of exotic ND
  • Removes the potential for respiratory reactions due to live ND vaccines
  • No vaccine reactions observed in safety trials for improved bird performance
  • Offers in ovo or subcutaneous injection to fit any vaccination schedule
  • Shown to be effective against standard and variant infectious bursal disease challenge

Many factors must be considered in determining the vaccination program for a particular farm or poultry operation. To be fully effective, the vaccine must be administered to healthy receptive birds held in proper environment under good management. In addition, the response may be modified by the age of the birds and their immune status. Seldom does 1 vaccination under field conditions produce complete protection for all individuals in a given flock. The amount of protection required will vary with the type of operation and the degree of exposure that a flock is likely to encounter.

In-ovo Administration:

  1. Inoculate each 18-day-old chicken embryo with a full dose (0.05 ml or 0.1ml).
  2. Entire contents of container must be used within 1 hour after mixing or be discarded according to caution statement No. 11.
  3. After reconstitution, the vaccine should be kept cool and gently agitated frequently.

Subcutaneous Administration:

  1. Hold the chicken by the back of the neck just below the head. The loose skin in the area is raised by gently pinching with the thumb and forefinger. Insert the needle beneath the skin in a downward direction away from the head. Inject 0.2 ml per chicken.
  2. Avoid hitting the muscles and bones in the neck.
  3. Entire contents of container must be used within 1 hour after mixing or be discarded according to caution statement No. 11.

1 x 4000 does ampules

Good management practices are recommended to reduce exposure to Marek’s disease and bursal disease for at least three weeks following vaccination. Therefore, directions should be followed carefully.

  1. Do not mix any substance with this vaccine. Do not mix with other products, except as specified on this label.
  2. Store vaccine in liquid nitrogen at a temperature below -150°C (-238°F).
  3. Gloves and visor should be worn when handling liquid nitrogen.
  5. Do not dilute or otherwise stretch the dosage of this vaccine.
  6. Once mixed with diluent, the vaccine should be gently agitated frequently.
  7. Once mixed with diluent, the vaccine should be used within 1 hour.
  8. Only healthy chicken embryos or chickens should be vaccinated.
  9. Do not vaccinate within 21 days before slaughter.
  10. This vaccine contains gentamicin as a preservative.
  11. Inactivate unused contents before disposal.
  12. In case of human exposure, contact a physician.

This vaccine has undergone rigid potency, safety and purity tests, and meets Merck Animal Health, U.S. and local regulatory requirements. It is designed to stimulate effective immunity when used as directed, but the user must be advised that the response to the product depends upon many factors, including, but not limited to, conditions of storage and handling by the user, administration of the vaccine, health and responsiveness of the individual chickens, and the degree of field exposure. A safety data sheet (SDS) is available upon request. This and any other consumer information can be obtained by calling Merck Animal Health Customer Service at 1-800-211-3573.

Keep a record of vaccine, quantity, serial number, expiration date, and place of purchase; the date and time of vaccination; the number, age, breed, and locations of chickens; names of operators performing the vaccination and any observed reactions.

Contact our sales or technical services representatives to help design a custom vaccination program.

closeup of green chicken feathers


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Demonstrated 60 weeks of protection against virulent Newcastle Disease challenge in combination with Rismavac®


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For additional information, please see the product label.
For more information regarding efficacy and safety data, go to

*Data on file, Merck Animal Health

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