#1 GnRH on the Market1

FERTAGYL® (gonadorelin) improves reproductive efficiency, specifically by synchronizing estrous cycles and treating cystic ovaries.


  • Treatment of cystic ovaries in dairy cattle
  • Use with ESTRUMATE® (cloprostenol injection) to synchronize estrous cycles to allow for fixed time artificial insemination (FTAI) in lactating dairy cows.
  • Use with cloprostenol sodium to synchronize estrous cycles to allow for FTAI in beef cows.

Dosage & Administration

  • Each mL of FERTAGYL contains 43 mcg gonadorelin.
  • For treatment of cystic ovaries: 2 mL per cow via intravenous or intramuscular injection.
  • For estrous synchronization: 2 mL per cow via intravenous or intramuscular injection. See package insert for complete dosing regimen.
  • Available in 100 mL and 20 mL bottles.


FERTAGYL is a gonadorelin acetate and acts on the hypothalmus causing release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) to cause ovulation and luteinization. Research has shown FERTAGYL produces high ovulation rates and pregnancies per AI (artificial insemination).

Ovulation and Fertility Response to GnRH Products_Luchterhand et al


Comparison of GnRH Products in Lactating Dairy Cows_Souza et al


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Join many other dairy and beef cattle producers in using the #1 GnRH on the market

There are many options for synchronization of estrus and ovulation in cattle, so consult your veterinarian to select an appropriate program for your operation.

To increase your herd’s reproductive efficiency, choose a synchronization program that includes both FERTAGYL and ESTRUMATE.

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Not for use in humans. Keep out of reach of children.

Women of childbearing age, asthmatics, and persons with respiratory problems should exercise extreme caution when handling Estrumate. Estrumate is readily absorbed through the skin and may cause abortion and/or bronchospasms; direct contact with the skin should be avoided and accidental spillage on the skin should be washed off immediately with soap and water. Do not administer Estrumate to a pregnant cow if abortion is not desired. Severe localized post-injection clostridial infections have been eported; in rare instances infection has led to death. At 50 and 100 times the recommended dose, mild side effects may be detected. For complete information on Estrumate, see package insert.

1 Animalytix, MAT July 2020